Meet the 2025 Nobel laureates in Physiology
What they won the Nobel Prize for
Mary E. Brunkow
Fred Ramsdell
Shimon Sakaguchi
The takeaway
The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their groundbreaking discoveries in peripheral immune tolerance—a mechanism that prevents the immune system from attacking the body’s own tissues.
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