President Donald Trump on Tuesday announced a multipronged effort aimed at lowering drug costs in the United States, including the creation of a “TrumpRx” direct-to-consumer website where Americans can buy medicine at discounted prices and a sweeping deal with Pfizer to reduce the prices of many of its products.

“The United States is done subsidizing the health care of the rest of the world,” Trump said at a news conference. “By taking this bold step, we’re ending the era of global price gouging at the expense of American families.”

Pfizer is the first drugmaker to voluntarily agree to all the demands Trump laid out in a July letter to pharmaceutical company CEOs. The president signaled others might soon follow.

Pfizer will sell drugs to Medicaid and set prices of new drugs at “Most Favored Nation” levels, the lowest price made available in peer countries. It will sell many of its primary care medicines and some specialty brand-name drugs at a 50% savings, on average, at TrumpRx, the company said. And it will expand its domestic manufacturing, while receiving a three-year reprieve on certain tariffs on pharmaceutical imports.

The TrumpRx site, which will not go live until early 2026, will not sell or distribute medications, a senior administration official told reporters Tuesday.

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