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More than 420 anti-science bills attacking longstanding public health protections – vaccines, milk safety and fluoride – have been introduced in statehouses across the U.S. this year, part of an organized, politically savvy campaign to enshrine a conspiracy theory-driven agenda into law.

An Associated Press investigation found that the wave of legislation has cropped up in most states, pushed by people with close ties to Health and Human Services Secretary Robert F. Kennedy Jr. The effort would strip away protections that have been built over a century and are integral to American lives and society. Around 30 bills have been enacted or adopted in 12 states.

Trump administration officials are directing activists to push anti-science legislation in the states – where public health authority rests – with the ultimate goal of changing laws and minds nationally.

The effort normalizes ideas fueled by the anti-vaccine movement that Kennedy has helped lead for years. His Make America Healthy Again agenda masks anti-science ideas while promoting goals such as making food more natural or reducing chemicals. Meanwhile, vaccination rates continue to fall, allowing the infectious diseases measles and whooping cough to make comebacks as Kennedy has sought to broadly remake federal policies on public health matters including fluoride and vaccines.

Kennedy’s allies dispute that their agenda is anti-science or driven by conspiracy theories, but many experts disagree.

“The march of conspiracy thinking from the margins to the mainstream now guiding public policy should be a wake-up call for all Americans,” said Devin Burghart, president and executive director of the Institute for Research and Education on Human Rights, who has tracked the anti-vaccine movement for decades. “People are literally going to die from it as a result.”

Ashlee and Erik Dahlberg of Lowell, Indiana, lost their 8-year-old son, Liam, to a vaccine-preventable disease in April.

“I thought having the vaccines would protect our children,” Erik Dahlberg said. “Unfortunately, it did not because other kids, other adults, need to be vaccinated as well in order for it to work.”

Liam was particularly vulnerable because he had severe asthma and allergies.