Deaths caused by a synthetic opioid that is hundreds of times stronger than heroin may have been underestimated by up to a third across the UK, according to research.

Nitazenes are a class of synthetic opioids that are extremely potent, and up to 500 times stronger than heroin. They were manufactured originally as a painkiller in the 1950s but their development was halted due to their extreme potencies resulting in a high risk of addiction.

In 2024, the National Crime Agency (NCA) reported that 333 fatalities across the UK were linked to the drug.

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