My father, John Lewis, who has died aged 92, played a leading role in the development of buprenorphine, used successfully to treat millions of people worldwide as an alternative to morphine as a painkiller after operations, and later as an alternative to methadone, to treat opioid drug addicts.

He did this primarily in his role as research and development director at Reckitt & Colman pharmaceuticals (1965-89), and later at Bristol University, where he set up the Reckit

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